A urine sample with an orange to red hue, what should we do?

A urine sample submitted for a urinary calcium-to-creatinine ratio was visually clear but deep orange in color (Fig. 1, left). Acidification of the sample to pH 2.0 with HCl prior to analysis produced a color change in the sample from orange to deep red (Fig. 1, right). The 16-year-old female patient had a history of polycystic ovarian syndrome, oligomenorrhea, and vitamin D deficiency and a suspected urinary tract infection.